dSysMap (Mapping of Human disease-related mutations at the systemic level) displays Human disease-related mutations on the structural interactome. Mapping of mutations on protein structures and on interaction interfaces allows you to visualize the region of the interactome that they affect and helps in rationalizing their mechanism of action.
The current version of dSysMap is 2015_05
Is this you first time with dSysMap? Take a 5 minutes Tutorial!
Select a disease from the following list.
Example: Loeys-Dietz syndrome
Enter a list of proteins (Uniprot AC or gene name)
Please introduce a correct list of Uniprot ACs or gene
names, separated by spaces.
Also make sure that the Uniprot ACs that you have entered refer to the correct version of Uniprot.
Enter a list of mutations (which format?)